| 09/07/2022 | |||
| 2:50 pm | MBC from Down under (Friends from Australia, Virtual Session) Moderator: Jaime Fornetti, PhD, Huntsman Cancer Institute | ||
| 2:50 pm - 3:00 pm | Welcome and Conference Goals Speaker: Alana Welm, PhD, Huntsman Cancer Institute Speaker: Josh Newby, Theresa's Research Foundation; BCM | ||
| 3:00 pm - 3:20 pm | Parsing breast cancer ecosystems with cellular genomics Speaker: Alex Swarbrick, PhD, Garvan Institute of Medical Research | ||
| 3:20 pm - 3:40 pm | Targeting pro-survival proteins to enhance tumor response in breast cancer Speaker: Geoffrey Lindeman, BSc (Med), MBBS (Hons), FRACP, PhD, The Walter and Eliza Hall Institute of Medical Research | ||
| 3:40 pm - 4:00 pm | Agonizing over the androgen receptor in breast cancer Speaker: Amy Dwyer, PhD, University of Adelaide | ||
| 4:00 pm | BREAK | ||
| 5:00 pm - 7:00 pm | Poster Session, GRASP, Networking Reception (In person only) | ||
| 09/08/2022 | |||
| 8:00 am - 8:20 am | Welcome and Overview Speaker: Alana Welm, PhD, Huntsman Cancer Institute Speaker: Josh Newby, Theresa's Research Foundation; BCM | ||
| 8:20 am - 8:30 am | Patient Advocate Welcome Speaker: Carla Lloyd, PhD | ||
| 8:30 am | Session 1 Moderator: Alana Welm, PhD, Huntsman Cancer Institute | ||
| 8:30 am - 9:00 am | Keynote: Antibody Drug Conjugates: Optimal Chemotherapy Delivery for Advanced Breast Cancer Speaker: Hope Rugo, MD, UCSF | ||
| 9:00 am | Session 2 Moderator: Ben Park, MD, PhD, Vanderbilt University Medical Center | ||
| 9:00 am - 9:20 am | Speaker: Martine Piccart, MD PhD, Institute Jules Bordet | ||
| 9:20 am - 9:40 am | Multiplatform analysis of matched primary and metastatic breast tumors from the AURORA US Network identifies microenvironment features as drivers of metastasis, Speaker: Susana Garcia-Recio, UNC - Lineberger Cancer Center | ||
| 9:40 am - 10:00 am | Biology and vulnerabilities of circulating tumor cells Speaker: Nicola Aceto, PhD, ETH Zurich | ||
| 10:00 am - 10:20 am | Characteristics of long-term survivors with metastatic breast cancer Speaker: Mark E. Burkard, MD, PhD, University of Wisconsin-Madison | ||
| 10:20 am - 10:40 am | BREAK | ||
| 10:40 am | Session 3 Moderator: Max Krummel, PhD, UCSF | ||
| 10:40 am - 11:00 am | Impact of Age on Breast Cancer Heterogeneity and Progression Speaker: Sandra McAllister, PhD, Dana Farber/ Harvard Cancer Center | ||
| 11:00 am - 11:20 am | Macrophage heterogeneity in the metastatic microenvironment Speaker: Kaylee Schwertfeger, PhD, University of Minnesota | ||
| 11:20 am - 11:40 am | Identification of novel innate immune cell axes controlling immune responses to cancer Speaker: Kevin Barry, PhD, Fred Hutchinson Cancer Research Center | ||
| 11:40 am - 12:00 pm | Mechanosurveillance in Metastasis Speaker: Ekrem Emrah Er, PhD, University of Illinois Chicago | ||
| 12:00 pm - 2:00 pm | Lunch: Networking Session (In person only) | ||
| 2:00 pm | Session 4 Moderator: Heide Ford, PhD, University of Colorado | ||
| 2:00 pm - 2:20 pm | Tumor Zonation and Immune Microenvironments in Triple Negative Breast Cancer Speaker: Morag Park, PhD, McGill - Rosalind and Morris Goodman Cancer Centre | ||
| 2:20 pm - 2:40 pm | SIM2s/SEMA7A Regulation of a Pi3K Subunit Switch in ER+ Metastatic Breast Cancer Speaker: Weston Porter, PhD, Texas A&M University | ||
| 2:40 pm - 3:00 pm | Semaphorin 7a promotes metastasis in multiple subtypes of breast cancer Speaker: Traci Lyons, PhD, University of Colorado | ||
| 3:00 pm - 3:15 pm | BREAK | ||
| 3:15 pm - 4:00 pm | Lightening Talks 1 Moderator: Zachary Schafer, PhD, University of Notre Dame Speaker: Brooke Gates, HCI Speaker: Lily Baek, Baylor College of Medicine Speaker: Menusha Arumugam, Van Andel Institute Speaker: Shaheen Sikandar, University of California Santa Cruz Speaker: Santha Ranganathan, Baylor University | ||
| 4:00 pm - 4:15 pm | BREAK | ||
| 4:15 pm | Session 5 Moderator: Minetta Liu, MD, Mayo Clinic | ||
| 4:15 pm - 4:35 pm | Updates in HR+ and Triple negative metastatic breast cancer Speaker: Claudine Isaacs, MD, Lombardi Comprehensive Cancer Center - Georgetown University | ||
| 4:35 pm - 4:55 pm | Updates in HER2+ metastatic breast cancer Speaker: Antonio Wolff, MD, Johns Hopkins University | ||
| 4:55 pm - 5:05 pm | Wrap Up | ||
| 5:30 pm | MBCRC Reception | ||
| 09/09/2022 | |||
| 7:50 am - 8:00 am | Patient Advocate Welcome Speaker: Janice Cowden | ||
| 8:00 am - 8:30 am | Session 6 Keynote: Rethinking Endocrine Therapies in Breast Cancer Speaker: Donald McDonnell, PhD, Duke University Moderator: Xiang Zhang, PhD, Baylor College of Medicine | ||
| 8:30 am | Session 7 Moderator: Senthil Muthuswamy, PhD, Harvard Medical School | ||
| 8:30 am - 8:50 am | Identification of an oncogene and niche-dependent early dissemination and dormancy driver mechanism in breast cancer models Speaker: Julio Aguirre-Ghiso, PhD, Albert Einstein Cancer Center | ||
| 8:50 am - 9:10 am | Understanding Tumor Heterogeneity to Reveal Actionable Targets for Metastatic Breast Cancer. Speaker: Andrei Goga, MD, PhD, UCSF | ||
| 9:10 am - 9:30 am | Molecular and cellular mechanisms of metastatic colonization Speaker: Momo Bentires-Alj, PhD, University of Basel | ||
| 9:30 am - 9:45 am | BREAK | ||
| 9:45 am - 11:00 am | Session 8 Speaker: Hillary Stires, PhD, Friends of Cancer Research Moderator: Alana Welm, PhD, Huntsman Cancer Institute Moderator: Josh Newby, Theresa's Research Foundation; BCM | ||
| 11:00 am | Session 9 Moderator: Steffi Oesterreich, PhD, University of Pittsburgh | ||
| 11:00 am - 11:20 am | Discovery of Colchicine Binding Site Inhibitors Targeting Tubulin to Overcome Taxane Resistance in Metastatic Breast Cancer Speaker: Tiffany Seagroves, MBA, PhD, University of Tennessee | ||
| 11:20 am - 11:40 am | Targetable Dependencies of Latent Brain Metastatic Cells Speaker: Srinivas Malladi, PhD, UT Southwestern | ||
| 11:40 am - 12:00 pm | Neutrophil elastase: an emerging therapeutic approach in breast cancer Speaker: Lev Becker, PhD, University of Chicago | ||
| 12:00 pm - 1:00 pm | LUNCH | ||
| 1:00 pm - 1:40 pm | Lightening Talks 2 Moderator: Mikala Egeblad, PhD, Cold Spring Harbor Labs Speaker: Khushali Patel, Baylor College of Medicine Speaker: Einav Nili Gal-Yam MD, PhD, Sheba Medical Center Speaker: Na Zhao, PhD, Baylor College of Medicine Speaker: Diana M. Cittelly, PhD, CU Anschutz Speaker: Lalita Shevde-Samant, UAB | ||
| 1:40 pm - 1:55 pm | BREAK | ||
| 1:55 pm | Session 10 Moderator: Jeff Rosen, PhD, Baylor College of Medicine | ||
| 1:55 pm - 2:15 pm | Discovering the way out: Spatiotemporal discovery of therapeutic pathways from healing wounds Speaker: Max Krummel, PhD, UCSF | ||
| 2:15 pm - 2:35 pm | Epigenetic modulatory function of osteogenic cells in metastasis progression Speaker: Igor Bado, PhD, Mount Sinai | ||
| 2:35 pm - 2:55 pm | Patient-derived models of breast cancer for discovery science and precision medicine Speaker: Alana Welm, PhD, Huntsman Cancer Institute | ||
| 2:55 pm - 3:15 pm | Therapeutic targeting of cancer fitness gene MTDH in metastatic breast cancer. Speaker: Yibin Kang, PhD, Princeton | ||
| 3:15 pm - 3:30 pm | BREAK | ||
| 3:30 pm | Session 11 Moderator: Andrew Ewald, PhD, Johns Hopkins University | ||
| 3:30 pm - 3:50 pm | Accelerating Precision Oncology in Metastatic Breast Cancer through Translational Genomics and Patient Partnered Research Speaker: Nick Wagle, MD, Broad Institute | ||
| 3:50 pm - 4:10 pm | Proteogenomic landscape of chemotherapy resistance in TNBCs : Learning from patient biopsies Speaker: Meenakshi Anurag, PhD, Baylor College of Medicine | ||
| 4:10 pm - 4:30 pm | Micro-ecosystem of breast tissue and targeting new vulnerability Speaker: Bora Lim, MD, Baylor College of Medicine | ||
| 4:30 pm - 4:35 pm | CLOSING | ||
| 4:35 pm | Adjourn | ||
