HTRS 2021 Scientific Symposium
VIRTUAL MEETING AGENDA (Revised Feb 2021)
FWGBD Colloquium: March 9 |
Multidisciplinary Pre-Conference: March 10-11 |
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HTRS Scientific Symposium: March 10-12 |
MONDAY, MARCH 8, 2021
HTRS Research Colloquium: Day 1 – separate registration required
Eastern Time |
Event |
12:30 PM – 1:00 PM ET |
PRE-MEETING NETWORKING “BRING YOUR OWN LUNCH” |
1:00 PM ET |
OPENING REMARKS Wolfgang Bergmeier, PhD, and Margaret V. Ragni, MD, MPH, 2021 Colloquium Co-Chairs |
1:05 PM – 1:50 PM ET |
PLENARY SESSION: “HOW DO I BEGIN, AND WHO IS GOING TO PAY FOR THIS?” RESEARCH FUNDING TRENDS AND OPPORTUNITIES Moderator: Margaret V. Ragni, MD, MPH Speaker: Andrei Kindzelski, MD, National Institutes of Health (NIH) |
1:50 PM – 2:20 PM ET |
NETWORKING BREAK -OR- MENTORING SESSIONS |
2:20 PM – 3:20 PM ET |
PANEL PRESENTATION: “GETTING A JOB – A RECRUITER’S PERSPECTIVE” Moderator: Wolfgang Bergmeier, PhD |
2:20 PM |
BASIC SCIENCE PERSPECTIVE James Morrissey, PhD, Professor, University of Michigan |
2:35 PM |
CLINICAL SCIENCE PERSPECTIVE Janis Abkowitz, PhD, Professor, Hematology Division Head, University of Washington |
2:50 PM |
TRANSLATIONAL SCIENCE PERSPECTIVE Jorge Di Paola, MD, Professor/Division Chief, Washington University in St. Louis |
3:05 PM |
INDUSTRY PERSPECTIVE Robert Peters, PhD, Sanofi Genzyme |
3:20 PM – 4:00 PM ET |
ROUNDTABLE DISCUSSIONS
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4:00 PM ET |
DAY ONE PROGRAM ENDS Session resumes Tuesday, March 9 at 12:30 PM ET |
TUESDAY, MARCH 9, 2021
FWGBD Colloquium on Uterine Hemostasis – separate registration required
Eastern Time |
Event |
9:30 AM – 9:45 AM ET |
CONVENE AND WELCOME
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9:45 AM – 9:55 AM ET |
UTERINE HEMOSTASIS OVERVIEW |
9:55 AM – 10:15 AM ET |
WOMEN & GIRLS WITH HEMOPHILIA Sarah H. O’Brien, MD, MSc |
10:15 AM – 10:30 AM ET |
BREAK |
10:30 AM – 11:00 AM ET |
MANAGEMENT OF DELIVERY IN WOMEN WITH HEMOPHILIA Andra H. James, MD, MPH |
11:00 AM – 11:30 AM ET |
RISK OF CLOTTING ON HORMONAL THERAPY Naomi Tepper, MD, MPH |
11:30 AM – 12:05 PM ET |
IS IT HELLP SYNDROME? IS IT TTP? IS IT ATYPICAL HUS? DOES IT MATTER? Gowthami Arepally, MD |
12:05 – 12:30 PM ET |
DISCUSSION AND WRAP-UP |
TUESDAY, MARCH 9, 2021 – continued
HTRS Research Colloquium: Day 2 – separate registration required
Eastern Time |
Event |
12:30 PM – 1:00 PM ET |
PRE-MEETING NETWORKING “BRING YOUR OWN LUNCH” |
1:00 PM – 1:05 PM ET |
DAY TWO - OPENING REMARKS Ming Y. Lim, MD/MBBCH, MSCr, and Joshua Muia, PhD, 2021 Colloquium Planning Committee Members |
1:05 PM – 1:50 PM ET |
PLENARY SESSION: “CRITICAL STEPS FOR A SUCCESSFUL CAREER IN ACADEMIC MEDICINE” Moderator: Mary Cushman, MD, MSc Speaker: Mark T. Gladwin, MD, Jack D. Myers Distinguished Professor and Chair, Chairman of the Department of Medicine, UPMC and the University of Pittsburgh School of Medicine |
1:50 PM – 2:10 PM ET |
BREAKOUT SESSION 1: “PRACTICAL TOOLS EVERYONE NEEDS TO ADVANCE THEIR CAREERS” |
BREAKOUT 1 |
SPEAK UP: GIVING EFFECTIVE PRESENTATIONS Discussion Leader: Alisa S. Wolberg, PhD |
BREAKOUT 2
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MANAGING THE K-TO-R TRANSITION: WHAT TO DO IF YOU DON’T GET A K-AWARD Discussion Leader: Nigel Key, MB, ChB, FRCP |
BREAKOUT 3 |
FROM GOOD IDEA TO SUBMITTED GRANT Discussion Leader: Gowthami Arepally, MD |
BREAKOUT 4
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BEGIN AGAIN: JUMP START YOUR RESEARCH CAREER AFTER A BREAK Discussion Leader: Menaka Pai, BSc, MSc, MD, FRCPC |
2:10 PM – 2:30 PM ET |
“GET UP AND STRETCH BREAK’ -OR- MENTORING SESSIONS |
2:30 PM – 2:50 PM ET |
BREAKOUT SESSION 2: “PRACTICAL TOOLS EVERYONE NEEDS TO ADVANCE THEIR CAREERS” |
BREAKOUT 1 |
SPEAK UP: GIVING EFFECTIVE PRESENTATIONS Discussion Leader: Alisa S. Wolberg, PhD |
BREAKOUT 2
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MANAGING THE K-TO-R TRANSITION: WHAT TO DO IF YOU DON’T GET A K-AWARD Discussion Leader: Nigel Key, MB, ChB, FRCP |
BREAKOUT 3 |
FROM GOOD IDEA TO SUBMITTED GRANT Discussion Leader: Gowthami Arepally, MD |
BREAKOUT 4
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BEGIN AGAIN: JUMP START YOUR RESEARCH CAREER AFTER A BREAK Discussion Leader: Menaka Pai, BSc, MSc, MD, FRCPC |
2:50 PM – 3:35 PM ET |
PANEL PRESENTATION: “OVERCOMING OBSTACLES: MOVING YOUR CAREER FORWARD” Moderator: Rodney Camire, PhD |
2:50 PM |
BASIC/TRANSLATIONAL SCIENCE PERSPECTIVE Veronica H. Flood, MD |
3:05 PM |
CLINICAL SCIENCE PERSPECTIVE Margaret V. Ragni, MD, MPH |
3:20 PM |
INDUSTRY PERSPECTIVE Marcus Carr, MD |
3:35 PM – 4:20 PM ET |
CLOSING RECEPTION “BRNG YOUR OWN SNACKS |
4:20 PM ET |
DAY TWO PROGRAM ENDS |
WEDNESDAY, MARCH 10, 2021
HTRS Multidisciplinary Pre-Conference: Day 1 – separate registration required
Eastern Time |
Event |
10:00 AM – 10:05 AM ET |
DAY ONE - OPENING REMARKS Loren D’Angelo, RN-BC, BSN, MSN, CPNP-PC, HTRS 2021 Planning Committee |
10:05 AM – 11:30 AM ET |
PRE-CONFERENCE SESSION 1: “NEW THERAPIES” Moderators: Loren D’Angelo, RN-BC, BSN, MSN, CPNP-PC, and Caitlin Moncrieff, NP |
10:05 AM |
DOACS IN THE PEDIATRIC POPULATION Riten Kumar, MD, MSc |
10:35 AM |
MANAGING INHIBITORS IN THE REALM OF NON-FACTOR THERAPIES James Munn, RN-BC, BS, BSN, MS |
10:55 AM |
“GENE THERAPY CLINICAL TRIAL EXPERIENCES IN CARE” Darcy Phelan, NP, MSN |
11:20AM |
Live Q&A |
11:30 AM |
DAY ONE PROGRAMMING ENDS Session resumes Thursday, March 11 at 10:00 AM ET |
WEDNESDAY, MARCH 10, 2021
HTRS Scientific Symposium: Day 1
Eastern Time |
Event |
12:00 PM – 1:00 PM ET |
SATELLITE SYMPOSIA: (2) Concurrent Sessions Sanofi Genzyme: "siRNA Technology in Hemophilia" Presenters: Guy Young, MD |
1:00 PM – 1:05 PM ET |
OPENING REMARKS Jordan Shavit, MD, PhD, HTRS 2021 Planning Committee Chair Ayesha N. Zia, MD, HTRS 2021 Planning Committee Vice Chair |
1:05 PM – 2:30 PM ET
1:10 PM – 1:20 PM
1:20 PM – 1:25 PM
1:25 PM – 1:40 PM
1:40 PM – 1:55 PM
1:55 PM – 2:05 PM
2:05 PM – 2:15 PM
2:15 PM – 2:25 PM
2:25 PM – 2:30 PM
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SYMPOSIUM SESSION 1 DEBATE: “THE FUTURE OF HEMOPHILIA THERAPEUTICS: SUBSTITUTION OR GENE THERAPY?” Moderators: Jordan Shavit, MD, PhD and Yasmina Abajas, MD Speakers: Denise E. Sabatino, PhD, Michael Callaghan, MD, and Shawn Jobe, MD, PhD
Jordan Shavit, MD, PhD and Yasmina Abajas, MD
Introduction: “The science behind hemophilia therapeutics” Denise E. Sabatino, PhD
Pre-Debate ARS Vote Jordan Shavit, MD, PhD and Yasmina Abajas, MD
Argument for Substitution Michael Callaghan, MD
Argument for Gene Therapy Shawn Jobe, MD, PhD
Rebuttal for Substitution Michael Callaghan, MD
Rebuttal for Gene Therapy Shawn Jobe, MD, PhD
Questions/Discussion Jordan Shavit, MD, PhD and Yasmina Abajas, MD
Post-Debate ARS Vote Jordan Shavit, MD, PhD and Yasmina Abajas, MD |
2:30 PM – 3:30 PM ET |
NETWORKING & EXHIBITOR SPEED BREAK |
3:30 PM – 4:30 PM ET |
ORAL ABSTRACT PRESENTATIONS: (2) Concurrent Sessions |
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vWF/HEMOPHILIA A |
Novel Mechanisms & Trials |
3:30 PM |
“THE IMPORTANCE OF GENETIC TESTING IN DIAGNOSING VON WILLEBRAND'S DISEASE TYPE 2M” |
“PLATELETS FACTOR 4 (PF4) BINDING ENHANCES IN VITRO NEUTROPHIL EXTRACELLULAR TRAPS (NET) CAPTURE OF SARS-COV-2: THERAPEUTIC IMPLICATIONS” |
3:45 PM |
“VON WILLEBRAND FACTOR (VWF) MULTIPLEX ACTIVITY ASSAY DIFFERENTIATION OF LOW VWF/TYPE 1 VON WILLEBRAND DISEASE (VWD) AND VARIANT VWD: ANALYSIS FROM THE COMPARATIVE EFFECTIVENESS IN THE DIAGNOSIS OF VWD” Presenter: Jonathan C. Roberts, MD |
“IN VITRO-GROWN MEGAKARYOCYTES (MKS) TAKE UP THE ECTOPIC PROTEIN UROKINASE (UPA) AND THE RESULTING PLATELETS (PLTS) CAN RELEASE THE UPA AT SITES OF VASCULAR INJURY” Presenter: Sergei V. Zaitsev, PhD |
4:00 PM |
Non-CME Presentation: “BROAD PATIENT ELIGIBILITY AND LONG-TERM TOLERABILITY IN THE FIRST-IN-HUMAN GENE THERAPY STUDY OF AAVHU37.HFVIIICO IN SEVERE HEMOPHILIA A” Presenter: Francesca Ferrante, MD |
“BLEEDING DIATHESIS IN MICE LACKING JAK2 IN PLATELETS” |
4:15 PM |
Non-CME Presentation: “REAL-WORLD DATA FROM A US CLAIMS DATABASE AMONG PATIENTS WITH HEMOPHILIA A TREATED WITH RECOMBINANT FVIII FC FUSION PROTEIN” Presenter: Amanda Wilson, MPH, PhD |
“A RANDOMIZED, PRAGMATIC TRIAL TO ASSESS A PEDIATRIC REAL-TIME RISK PREDICTION MODEL FOR THROMBOTIC EVENTS” Presenters: Shannon C. Walker, MD |
4:30 PM - 5:30 PM ET |
OPEN NETWORKING |
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5:30 PM - 6:30 PM ET |
SATELLITE SYMPOSIA: (2) Concurrent Sessions Takeda: Presenter: Tammuella Chrisentery Singleton, MD |
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6:30 PM ET |
DAY ONE PROGRAMMING ENDSe General Session resumes Thursday, March 11 at 12:00 PM ET |
THURSDAY, MARCH 11, 2021
HTRS Multidisciplinary Pre-Conference: Day 2 – separate registration required
Eastern Time |
Event |
10:00 AM – 10:05 AM ET |
DAY TWO - OPENING REMARKS Loren D’Angelo, RN-BC, BSN, MSN, CPNP-PC, HTRS 2021 Planning Committee |
10:05 AM – 11:30 AM ET
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PRE-CONFERENCE SESSION 2: INCLUSIVE CARE Moderators: Mary Lesh, PNP, MSN and Caitlin Moncrieff, NP |
10:05 AM |
TRAUMA INFORMED CARE FOR HEMATOLOGY PROVIDERS Amanda Stahl, LICSW |
10:35 AM |
HEMATOLOGIC CONSIDERATIONS IN THE CARE OF TRANSGENDER PATIENTS Meredith Russel, PNP, MSN |
11:15 AM |
Live Q&A |
11:30 AM ET |
HTRS 2021 Multidisciplinary Pre-conference Ends |
THURSDAY, MARCH 11, 2021
HTRS Scientific Symposium: Day 2
Eastern Time |
Event |
12:00 PM – 1:00 PM ET |
SATELLITE SYMPOSIA: (2) CONCURRENT SESSIONS Novo Nordisk: "A rFVIIa with over 30 years of experience with treating hemophilia and other rare bleeding disorders" Presenters: Stephanie Seremetis, MD, Miguel Escobar, MD, and Joanna Davis, MD |
1:00 PM – 1:05 PM ET |
OPENING REMARKS Jordan Shavit, MD, PhD, HTRS 2021 Planning Committee Chair Ayesha N. Zia, MD, HTRS 2021 Planning Committee Vice Chair |
1:05 PM – 2:10 PM ET
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SYMPOSIUM SCIENTIFIC SESSION 2: STATE-OF-THE-ART LECTURE: “COVID-19: THROMBOSIS AND CLINICAL CONSIDERATIONS” Moderator: Jordan A. Shavit, MD, PhD and Andrea Obi, MD, Co-moderator Speakers: Roger Lewis, MD, Robert Campbell, PhD, and Hanny Al-Samkari, MD |
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2:10 PM - 3:10 PM ET |
EXCLUSIVE SATELLITE SYMPOSIUM |
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3:10 PM – 4:10 PM ET |
ORAL ABSTRACT PRESENTATIONS: (2) Concurrent Sessions |
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THROMBOSIS and Rachel Rosovsky, MD |
HEMOPHILIA B and Janice Staber, MD |
3:10 PM |
“INVESTIGATING THE REGULATION OF RAP1-INTEGRIN SIGNALING PATHWAY USING THE IMMKCL MEGAKARYOCYTE MODEL” Presenter: Ankita Dhenge, PhD |
“AMT-060 GENE THERAPY IN ADULTS WITH SEVERE OR MODERATE-SEVERE HEMOPHILIA B CONFIRM STABLE FIX EXPRESSION AND SUSTAINED REDUCTIONS IN BLEEDING AND FACTOR IX USE FOR UP TO 5 YEARS” |
3:25 PM |
“FORMATION OF PROTHROMBINASE ON HUMAN ENDOTHELIAL CELLS” Presenter: Clay T. Cohen, MD |
“ETRANACOGENE DEZAPARVOVEC (AAV5-PADUA HFIX VARIANT), AN ENHANCED VECTOR FOR GENE TRANSFER IN ADULTS WITH SEVERE OR MODERATE-SEVERE HEMOPHILIA B: TWO YEAR DATA FROM A PHASE 2B TRIAL” |
3:40 PM |
“HEMATOLOGIC ABNORMALITIES AND VENOUS THROMBOPROPHYLAXIS IN MIS-C: DATA FROM A MULTI-DISCIPLINARY WORKING GROUP AT A PEDIATRIC TERTIARY CARE HOSPITAL” Presenter: Lynn M. Malec, MD, MSc |
“EFFICACY AND SAFETY OF ETRANACOGENE DEZAPARVOVEC IN ADULTS WITH SEVERE OR MODERATE-SEVERE HEMOPHILIA B: FIRST DATA FROM THE PHASE 3 HOPE-B GENE THERAPY TRIAL” |
3:55 PM |
“RISK OF VENOUS THROMBOEMBOLISM IN PEDIATRIC HOSPITALIZED PATIENTS UNDERGOING NON-CARDIAC SURGERY, A REPORT FROM THE CHILDREN'S HOSPITAL-ACQUIRED THROMBOSIS (CHAT) CONSORTIUM” |
Non-CME Presentation: “CLEARANCE OF FIDANACOGENE ELAPARVOVEC VECTOR DNA IN PATIENTS WITH SEVERE OR MODERATELY SEVERE HEMOPHILIA B (HB)” Presenter: Patrick F. Fogarty, M |
4:10 PM – 4:15 PM ET |
TRANSITION TO REMO |
4:15 PM – 5:15 PM ET |
POSTER PRESENTATIONS + SPEED SESSIONS
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5:15 PM – 6:15 PM ET |
OPEN NETWORKING |
6:15 PM – 7:15 PM ET |
SATELLITE SYMPOSIA: 2 Concurrent Sessions Takeda (CME) | Novo Nordisk |
7:15 PM |
DAY TWO PROGRAMMING ENDS General Session resumes Friday, March 12 at 12:00 PM ET |
FRIDAY, MARCH 12, 2021
HTRS Scientific Symposium: Day 3
Eastern Time |
Event |
12:00 PM – 1:00 PM ET |
SATELLITE SYMPOSIA: (2) Concurrent Sessions Sanofi Genzyme: "A Breakthrough in aTTP Treatment: Now recommended by the ISTH Guidelines" Presenters: Jay Raval, MD |
1:00 PM – 1:05 PM ET |
OPENING REMARKS Jordan Shavit, MD, PhD, HTRS 2021 Planning Committee Chair Ayesha N. Zia, MD, HTRS 2021 Planning Committee Vice Chair |
1:05 PM – 2:10 PM ET
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SCIENTIFIC SESSION 3: “BENCH, CLINIC, AND EVERYTHING IN-BETWEEN” (3) Concurrent Sessions |
Session 3-A: “Platelets” |
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Session 3-B: “Sickle Cell-Associated Thrombosis” Speakers: Morey Blinder, MD, Erica Sparkenbaugh, PhD, Huanghe Yang, PhD |
Session 3-C: “Post-VTE Functional Syndromes” Moderators: Ayesha N. Zia, MD and Marisol Betensky, MD, MPH, Co-moderator |
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2:10 PM – 2:20 PM ET |
TRANSITION TO REMO |
2:20 PM – 3:20 PM ET |
NETWORKING & EXHIBITOR SPEED BREAK |
3:20 PM – 4:20 PM ET |
POSTER PRESENTATIONS AND SPEED SESSIONS
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4:20 PM - 4:30 PM ET |
INTRODUCTION TO CLOSING EXTRAVAGANZA |
4:30 PM - 5:30 PM ET |
CLOSING EXTRAVAGANZA NETWORKING & THE FIRST-EVER “HTRS TALENT SHOW” |
5:30 PM ET |
HTRS 2021 SCIENTIFIC SYMPOSIUM PROGRAMMING ENDS
Mark your calendars for the next HTRS Scientific Symposium:
March 10 - 12, 2023 Renaissance Orlando at SeaWorld Orlando, FL
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Incorporated as a nonprofit in 1994, the Hemostasis and Thrombosis Research Society (“HTRS”) is a North American professional medical society dedicated to advancing care for people with bleeding and thrombotic disorders through investigator-initiated research, mentoring, and continuing medical education.
Phone: +1 856.471.7211
Email: contact@htrs2021.org
Website: www.htrs.org