Cancer-associated thrombosis (CAT) is a leading cause of morbidity and mortality among cancer patients, often occurring in those with clinically active malignancy but also as the first manifestation of disease. The symposium will delve into the pathophysiology of CAT, evaluate current management guidance, and explore emerging evidence. The expert panel will navigate attendees through key questions such as risk assessment and tailoring approaches to anticoagulation therapy for individual patients. If you are planning to attend in person you must be registered for ISTH 2023.