Program Description

 

The 29th International Dynamics & Evolution of Human Viruses conference will be held June 22-24, 2022 at the Sanford Consortium in La Jolla California. This will be a hybrid meeting, which will include a live in person meeting and a virtual option.

This meeting series was designed to promote discussion between specialists in quantitative and computational approaches in two areas in the field of virology where these are particularly important:

  1. Modeling of viral and cellular dynamics
  2. Viral evolution and population genetics

Many of these approaches were originally developed for HIV but are now applied to many viruses where extensive data are available. We encourage the submission of abstracts relating to work on HIV, SARS-CoV-2 and other human viruses. We consider topics on statistical, mathematical, computational, and integrative approaches to analyzing the dynamics and evolution of human viruses within the scope of this meeting.

Abstracts are being submitted under the following topics from which the final conference schedule will be constructed:

  • Genomic Sequencing & Bioinformatics
  • Vaccines & Immunology
  • Software Tools & Methods
  • Origins & Emergence
  • Transmission Dynamics & Clusters
  • Within Host Dynamics

We actively encourage participation of researchers from around the globe, including junior scientists and members of minority groups.

 

We will continue to accept abstract submissions for posters until April 30, 2022.

Program Chairs


Joel Wertheim, PhD, University of California San Diego

Tetyana Vasylyeva, PhD, University of California San Diego

Location


Sanford Consortium

2880 Torrey Pines Scenic Drive

La Jolla, CA 92037

(858) 246-1076

 

For directions, please CLICK HERE. 

The Sanford Consortium is located within walking distance from the campus apartments.  Parking is available for a fee on-site.

Accommodations 

North Torrey Pines Living Learning Neighborhood

University of California San Diego

Muir College Drive

La Jolla, CA 92037

 

Campus housing will be provided at the North Torrey Pines Living and Learning Neighborhood.  Accommodations include a private bedroom with shared bathroom in a

campus apartment.  Breakfast and Dinner will be provided in the dining hall.  Lunches, breaks and the poster sessions will be held at the Sanford Consortium.

 

Agenda

*All times are in PDT

Tuesday, June 21, 2022

3:00 pm Registration

5:00 pm Welcome Reception

Wednesday, June 22, 2022

6:45 am Breakfast at Dining Hall

8:00       Welcome & Introductions

GENOMIC SEQUENCING & BIOINFORMATICS 

Session Chairs: Aine O’Toole & Thomas Leitner

8:05       GENOME-FIRST APPROACH TO THE DETECTION OF EMERGING RESISTANCE TO NOVEL THERAPEUTIC AGENTS FOR SARS-COV-2, *Manon Ragonnet-Cronin

8:30       SINGLE-CELL DNA SEQUENCING PROVIDES IMPROVED RESOLUTION OF RESERVOIR CONTRIBUTION TO VIRAL EVOLUTION, *Lauren Droske

8:55       SURFACE EXPOSED VIRUS PROTEINS ARE NOT SO DIFFERENT AFTER ALL, *Sareh Bagherichimeh

9:20       DRIVERS OF ADAPTIVE EVOLUTION DURING CHRONIC SARS-COV-2 INFECTIONS, *Shari Harari

9:45       Break

ORIGINS & EMERGENCE I

Session Chairs:  Emma Hodcroft & Joel Wertheim

10:05     THE ORIGINS AND MOLECULAR EVOLUTION OF THE SARS-COV-2 LINEAGE B.1.1.7 IN THE UK , *Verity Hill

10:30     INTENSIFICATION AND RELAXATION OF SELECTION IN VIRUSES DURING ATTENUATION AND GAIN-OF-FUNCTION PASSAGE: IMPLICATIONS FOR THE ORIGINS OF THE 1977 H1N1 AND COVID-19 PANDEMICS, *Jennifer Havens

10:55     RECONSTRUCTION AND FUNCTIONAL CHARACTERIZATION OF THE ANCESTRAL NEF PROTEIN OF PRIMATE LENTIVIRUSES, *Abayomi Olabode

11:20     THE HUANAN MARKET WAS THE EPICENTER OF SARS-COV-2 EMERGENCE, *Mike Worobey

11:45     SARS-COV-2 EMERGENCE VERY LIKELY RESULTED FROM AT LEAST TWO ZOONOTIC EVENTS, *Jonathan Pekar

12:10 pm  Lunch

ORIGINS & EMERGENCE II

Session Chairs:  Michael Worobey & Verity Hill

1:00       DECIPHERING THE EVOLUTIONARY HISTORY OF THE HEPATITIS B VIRUS USING ANCIENT GENOMIC DATA AND RECOMBINATION-AWARE PHYLOGENETIC ANALYSES, *Arthur Kocher

1:25       EVOLUTIONARY DYNAMICS GIVING RISE TO NOROVIRUS GII.4 VARIANTS, *Michael Martin

1:50       HIV-1 GROUP M ENV GENETIC DIVERSITY SINCE 1980, *Eric Lewitus

2:15       TRACKING MUTATIONS RESPONSIBLE FOR HUMAN EMERGENCE OF INFLUENZA A VIRUSES *Spyros Lytras

2:40       Break

TRANSMISSION DYNAMICS & CLUSTERS - HIV

Session Chairs: Andrew Leigh-Brown & Tetyana Vasylyeva

2:55       ESTIMATING THE POTENTIAL TO PREVENT LOCALLY ACQUIRED HIV INFECTIONS IN A UNAIDS FAST-TRACK CITY, AMSTERDAM, *Alexandra Blenkinsop

3:20       THE EVOLUTIONARY FEATURES OF THE TRANSMITTED HIV VARIANT, *Lele Zhao

3:45       PHYLOGENETIC PRIORITIZATION OF HIV-1 TRANSMISSION CLUSTERS WITH VIRAL LINEAGE-LEVEL DIVERSIFICATION RATES, *Rachel Miller

4:10       THE AGE AND SEX DYNAMICS OF HETEROSEXUAL HIV TRANSMISSION IN ZAMBIA LARGELY FOLLOW TYPICAL PATTERNS OF SEXUAL MIXING IN YOUNG PEOPLE, *Matthew Hall

4:35       BIOMARKER AND SEQUENCE INFORMED TRANSMISSION HISTORY INFERENCE OF HIV-1 CRF01 IN SWEDEN *Erik Lundgren

5:00       DYNAMICS OF THE SUBTYPE D HIV EPIDEMIC IN UGANDA DRIVEN BY X4 TROPISM, *Heather Grant

5:25       Poster Session

7:15       Dinner at Dining Hall

Thursday, June 23, 2022

6:45 am  Breakfast at Dining Hall

TRANSMISSION DYNAMICS & CLUSTERS – SARS-COV-2

Session Chairs: Manon Ragonnet-Cronin & Jonathan Pekar

8:00       FACTORS AFFECTING SELECTION AND COMPETITION BETWEEN VARIANTS IN AN ONGOING EPIDEMIC,*Anjalika Nande

8:25       ESTIMATING OVERDISPERSION IN SARS-COV-2 THROUGH SEQUENCE CLUSTERS, *Emma Hodcroft

8:50       SARS-COV-2 LINEAGES: LESSONS LEARNED AND PERSPECTIVES FOR FUTURE EPIDEMIC TRACKING, *Aine O’Toole

9:15       DOMINANCE OF NEW VARIANTS DURING THE SARS-COV-2 EPIDEMIC IN SWITZERLAND, *Martina Reichmuth

9:40       Break

10:05     INTRODUCTION AND ESTABLISHMENT OF SARS-COV-2 GAMMA VARIANT IN NEW YORK CITY IN EARLY 2021, *Tetyana Vasylyeva

10:30     A GENOMICS APPROACH TO SERIAL INTERVALS IN COVID-19 TRANSMISSION CLUSTERS, *Jessica Stockdale

SOFTWARE, TOOLS & METHODS I                                                                                                                                   

Session Chairs: Art Poon & Andrew Magee

10:55     RASCL: RAPID ASSESSMENT OF SELECTION IN CLADES THROUGH MOLECULAR SEQUENCE ANALYSIS, *Alexander Lucaci

11:20     EFFICIENT RECONSTRUCTION OF VIRAL ANCESTRAL RECOMBINATION GRAPHS USING MAXIMUM AGREEMENT FORESTS, *David Rasmussen

11:45     COVARIATION OF VIRAL RECOMBINATION WITH SINGLE NUCLEOTIDE VARIANTS DURING VIRUS EVOLUTION REVEALED BY COVAMA, *Shiyi Wang

12:10     INFERRING TRANSMISSION DYNAMICS FOR EMERGING VIRUSES USING SEGREGATING SITES , *Yeongseon Park

12:35 pm  Lunch

SOFTWARE, TOOLS & METHODS II                                                                                                                                  

Session Chairs: Sergei Pond & Jennifer Havens

1:30       SCALABLE RANDOM-EFFECTS SUBSTITUTION MODELS FOR PHYLOGENETICS, *Andrew Magee

1:55       BAYROOT: A BAYESIAN PHYLOGENETIC APPROACH TO DATING HIV RESERVOIR SEQUENCES, *Art Poon

2:20       MODELING SITE-DEPENDENT EPISTATIC SELECTION IN A PHYLOGENETIC CONTEXT, *Stephen Shank

2:45       BBD: A BEAST2 PACKAGE FOR EXTENDING TIP DATE SAMPLING, *Bradley Jones

3: 10      TAKING A DEEP LEARNING APPROACH TO REAL-TIME HIV OUTBREAK DETECTION WITH GENETIC DATA,*Michael Kupperman

3:35       PHYLODYNAMIC BOOSTED REGRESSION FOR INFERENCE OF PATHOGEN FITNESS, *Lenora Kepler

4:00       Break

4:15       KEYNOTE: ELICITING BROADLY PROTECTIVE ANTIBODIES AGAINST SARBECOVIRUSES BY MOSAIC NANOPARTICLE VACCINATION, Pamela Bjorkman, PhD

5:15       Posters

7:15       Dinner at Dining Hall

Friday, June 24, 2022

6:45 am Breakfast at Dining Hall

8:00       Announcements

VACCINES & IMMUNOLOGY 

Session Chairs: Bethany Dearlove & Eric Lewitus

8:05       DISCOVERY & DEVELOPMENT OF THERAPEUTIC INTERFERING PARTICLES (TIPS): SINGLE-ADMINISTRATION SARS-COV-2 AND HIV ANTIVIRALS WITH HIGH BARRIERS TO THE EVOLUTION OF RESISTANCE, * Leor Weinberger

8:30       LOW HVTN 705 CLINICAL VACCINE EFFICACY DOES NOT RULE OUT HIGH PER-CONTACT VACCINE EFFICACY, *Paul Edlefsen

WITHIN HOST DYNAMICS

Session Chair: Josh Herbeck

8:55       SARS-CoV-2: HOW RELIABLE ARE ESTIMATES OF INFECTION TIMES AND OTHER PARAMETERS IN VIRAL DYNAMIC MODELS?, *Carolyn Zitzmann

9:20       ON THE ROLE OF IFN IN EARLY HIV REBOUND DYNAMICS AFTER ANALYTICAL TREATMENT INTERRUPTION *Ruian Ke

9:45       HIV-1 TRANSMITTED/FOUNDER HAS A REDUCED MUTATION RATE COMPARED TO CHRONIC STRAINS,*Adam Nitido

10:15     Break

10:30     MACHINE LEARNING PREDICTION AND PHYLOANATOMIC MODELING OF VIRAL NEUROADAPTIVE SIGNATURES IN THE MACAQUE MODEL OF HUMAN IMMUNODEFICIENCY VIRUS-MEDIATED NEUROPATHOLOGY, *Andrea Ramirez-Mata

10:55     MATHEMATICAL MODELING OF ARVS DIFFUSION INTO THE LYMPH NODES TO INVESTIGATE DRUG TRANSPORT MECHANISMS, *Ryan Zurakowski

11:20     ESTIMATING HIV PROVIRAL INTEGRATION DATES WITH BEAST2, *Bradley Jones

11:45     CAPTURING INTRAHOST RECOMBINATION OF SARS-COV-2 DURING SUPERINFECTION WITH ALPHA AND EPSILON VARIANTS IN NEW YORK CITY,                *Joel Wertheim

12:10     Final Adjournment

 

Registration

 

The fee for this live program includes registration and workshop materials, accommodations for 3 nights and all meals. Apartments with private rooms and a shared bathroom have been reserved at the North Torrey Pines Living and Learning Neighborhood on campus. The meeting venue for 2022 is the Conference room at the Sanford Consortium. The Sanford Consortium is located within walking distance of the campus apartments. Parking is available for a fee at both locations.

                                                                                                       

Registration Fees

On or before 

5/20/2022

On or after

5/21/2022

Industry & Professors

Virtual Meeting

 $200 $250

Postdoctoral Fellows

Virtual Meeting

 $100 $150

Students

Virtual Meeting

 $50 $75

Registration & Accommodation

Private Bedroom with shared bathroom

 $875 $975

Registration Fee Only (Local participants)

Includes meeting materials, welcome reception, lunch, breaks

and poster sessions

 $395 $495

                                                                                                

Additional Nights - Room & Meals  
Monday, June 20, 2022  $105 
There are currently no room nights available for June 24th.  

Online registration closes June 15, 2022

 

Payment Accepted: Checks, Credit Card, Wire or UC Recharge only

Checks must be in US dollars, drawn on a US bank and made payable to UC REGENTS.

Paying by check? Please mail to:

UC San Diego School of Medicine
Continuing Medical Education
9500 Gilman Drive, MC0947
La Jolla, CA 92093-0947  

Check payments: Must be mailed by June 10, 2022 to ensure we get payment prior to start of program.

Wire Transfers: If you plan on processing a wire transfer to cover your registration fees, please email our CME Administrator, Carissa Aguayo at caguayo@health.ucsd.edu, directly to start the process.

 

Special Needs: Advance notice of special needs and/or dietary restrictions is requested at least two (2) weeks prior to the activity start date.

Contact Maureen Helinski Clarke at mhelinsk@health.ucsd.edu to submit your request.

 

Cancellation Policy

 

The full course tuition is refundable, less $75 if your cancellation is received in writing, on or before June 1, 2022. No refunds will be allowed after this date.

In the unlikely event that the course is canceled, the conference organizers are responsible only for a full refund of the registration fee.

For further information please contact us at ocme@health.ucsd.edu.

 

COVID-19 Health & Safety

We follow state and local guidelines and protocols related to COVID-19 safety measures. Due to the high risk for transmission in indoor settings, attendees will be required to wear a facemask indoors, regardless of vaccination status. Individuals who fail to comply will not be able to participate. In such a situation, no refunds of registration fees or other venue/travel related expenses will be provided.
 
A key method to reduce transmission at both indoor and outdoor events is to verify that attendees are fully vaccinated or have recently tested negative for COVID-19.
 
Attendees are required to provide a negative PCR test 48 hours prior to arrival and a negative test within 2 days after arrival.
 
 

More information will be sent with your registration confirmation.