April 2024
Frontotemporal Dementia & Emerging Therapies for Dementia
Bruce Miller, M.D. | A.W. and Mary Margaret Clausen Distinguished Professorship in Neurology, The University of California, San Francisco
Systemic Regulation of Brain Aging and Function
Tony Wyss-Coray, Ph.D. | D.H. Chen Professor of Neurology, Stanford University School of Medicine
Sleep and the Pathophysiology of Alzheimer's Disease
David Holtzman, M.D. | Andrew B. and Gretchen P. Jones Professor and Chair of Neurology, Washington University in St. Louis
Redefining Microglia States and Function in Alzheimer’s Disease
Beth Stevens, Ph.D. | Associate Professor of Neurology, Harvard Medical School in the FM Kirby Neurobiology Center at Boston Children's Hospital
Structural Classifications of Tauopathies
Marc Diamond, M.D. | Founding Director, Center for Alzheimer's and Neurodegenerative Diseases & Professor of Neurology and Neurotherapeutics, UT Southwestern
Gamma Oscillations: Mechanisms and Function in Human Neurodegenerative Diseases
Li-Huei Tsai, Ph.D. | Director, The Picower Institute for Learning and Memory at MIT; Picower Professor of Neuroscience, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology; Senior Associate Member, Broad Institute
Transposable Element Activation in Neurodegenerative Tauopathy: From Bench to Bedside
Bess Frost, Ph.D. | Bartell Zachry Distinguished Professor for Research in Neurodegenerative Disorders at the Barshop Institute for Longevity and Aging Studies, the Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Disorders, and the Department of Cell Systems and Anatomy at the University of Texas Health San Antonio
Neural Basis of a Silent Alzheimer's Disease Phase
Inna Slutsky, Ph.D. | Chair, Department of Physiology and Pharmacology, Sackler Faculty of Medicine at Tel Aviv University, Israel.
Exploring Genetic Studies on Human Neurodegenerative Diseasestotemporal Dementia & Emerging Therapies for Dementia
Peter Henry St George-Hyslop, M.D., FRCPC, FRS | Professor of Neurology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University
Tangles: Unravelling What We Don't Know About Tau
Karen Duff, Ph.D.| Centre Director of the UK Dementia Research Institute at University College London
In 1907, Oskar Fischer, a psychiatrist and neuropathologist in Prague, published pathological findings from 16 cases of “senile” dementia, describing the amyloid plaques and neurofibrillary tangles that are the pathological hallmarks of the condition now known as Alzheimer’s disease. Fischer followed up in 1910 with a comprehensive clinico-pathological study of 275 brains that included controls of various ages and pathologies.
That same year, Emil Kraepelin, director of the psychiatric clinic in Munich where Alois Alzheimer worked, named the disease in his textbook of psychiatry after Alzheimer, who had reported a single case in a short publication in 1907. Even so, over the next several years, plaques were referred to as “Fischer’s plaques.”
In 1919, Fischer left his research position at the German University in Prague and by 1939 was no longer allowed to teach there. He was arrested by the gestapo in 1941 and sent to the “political prison” in Terezin, where he died one year later at age 65.