Professor of Biochemistry and Molecular Biology
University of Arkansas for Medical Sciences
Dr. Tackett’s laboratory focuses on histone epigenetic mechanisms that regulate gene transcription and that are coupled to melanoma progression. His group utilizes a suite of techniques in their studies including proteomics of human biopsies, immunohistochemistry, cell culture, tumorigenicity assays, ChIPseq, biochemical and proteomic approaches for analyses of protein complexes, and cutting-edge mass spectrometry for the analysis of histone post-translational modifications. In addition to their melanoma work, Dr. Tackett’s group develops new technologies for epigenetic studies such as tools for detection of in vivo protein interactions and quantitative assays for histone-modifying proteins. Dr. Tackett serves as co-Director of the IDeA National Resource for Proteomics and Director of a Phase I COBRE, the Center for Translational Pediatric Research.